The Amtrak Southwest Chief, Train 4, derailed eight cars about 20 miles west of Dodge City, Kan., just after midnight today.
The train was en route from Los Angeles to Chicago. Delays are expected in some other Amtrak schedules today.
An Amtrak spokesman said there were 131 passengers and 14 crew members aboard the train, which had two locomotives and nine cars.
About 32 persons were taken to hospitals, and 29 were discharged this morning, according to Amtrak.
The crash is under investigation by the NTSB and Amtrak. Friends and family of those aboard the train may call 800-523-9101 for information.